Even in clinical trials, Lotronex displayed a tendency towards causing ischemic colitis in patients. From the February in which Lotronex was approved until June, the FDA received seven reports of serious complications of constipation leading to hospitalization. Surgery was required to relieve some cases of extreme Lotronex constipation. Lotronex Medication Guides were issued under regulations that became effective in 1999 when Lotronex patients ended up in hospitalization and requiring surgical procedures for constipation. Since Lotronex is a drug used to treat diarrhea, these surgeries were obviously not necessary to treat conditions held before taking the drug.
Despite the FDA's issuing of this safety information about Lotronex, patients kept filing severe adverse event reports of ischemic colitis, complications of constipation, death reports, and complications requiring blood transfusions. The FDA recalled Lotronex on November 2000, just nine months after approval.
In 2002, the FDA announced the approval of a supplemental New Drug Application that allows restricted marketing of Lotronex to treat only women with severe diarrhea-predominant irritable bowel syndrom. The approval of Lotronex includes a risk management program to ensure patients and physicians are fully informed of risks and possible benefits of Lotronex. Patients using Lotronex must sign a contract with their doctors stating that they understand the risk of serious constipation that could result in surgery, blood transfusion, or death.
These restrictions are very tight because of the history of tragedies involving Lotronex and its potential to cause unusual, very painful death by constipation. Because of this it is imperative that Lotronex not be bought over the internet. The system through which patients sign a Lotronex contract with their doctor assures that everybody involved in the transaction is educated on all the dangers and benefits involved and prepared to accept responsibility for the consequences.
Please contact a lawyer if you have taken Lotronex during the time when it enjoyed unrestricted access to the market, between 1999-2000. Also contact a lawyer if you are currently taking Lotronex and have not signed a contract with your doctor, or feel that your physician is administering the drug improperly.
To find out why you need a Lotronex lawyer and read articles about dangerous drugs and Lotronex side effects, visit our website at hugesettlements.com.
If you have any questions or concerns about filing a Lotronex lawsuit, please contact a professional Lotronex attorney right away!
![]() Google News Updated : Fri, 05 Sep 2008 02:05:17 GMT Rescuers can't get aid to starving Haitian city - The Associated Press
The Associated Press - GONAIVES, Haiti (AP) - The convoy rumbled out of the UN base toward a flooded, starving and seething city Thursday, carrying some of the first food aid since Tropical Storm Hanna drowned Gonaives in muddy water three days ago. Sorrow and hunger overwhelm Haitian storm shelter At least 90 killed as tropical storm Hanna passes by Haiti Publ.Date : Fri, 05 Sep 2008 01:01:18 GMT Work by Hopkins team lights way to cancer 'milestone' - Baltimore Sun
Baltimore Sun - By Frank D. Roylance | frank.roylance@baltsun.com Researchers cataloging the genetic codes of deadly human brain and pancreatic cancers say they have found several dozen defective genes that appear to work in concert to set off the tumor growth that ... Gene trawl shows curing cancer harder than thought Genetic Mutations Linked to Deadly Cancers Publ.Date : Fri, 05 Sep 2008 00:10:52 GMT Roger Federer advances at US Open - Los Angeles Times
Los Angeles Times - Elise Amendola / AP Roger Federer of Switzerland defeated Gilles Muller of Luxembourg, 7-6 (5), 6-4, 7-6 (5), to reach the semifinals of the US Open. Federer Rolls Past Muller Federer's year of living defensively - Tennis Publ.Date : Thu, 04 Sep 2008 22:39:50 GMT Bush advised to back modest troop cuts in Iraq - Reuters
Reuters - By Andrew Gray WASHINGTON (Reuters) - Top US defense officials have recommended that President George W. Bush withdraw one combat brigade from Iraq but not until early next year, Pentagon sources said on Thursday. Military officials: No troop cuts this year Sources: Bush advised to delay troop cuts in Iraq Publ.Date : Fri, 05 Sep 2008 00:06:35 GMT GOP Convention Spin, Part II - Newsweek
Newsweek - Palin trips up on her facts, and Giuliani and Huckabee have their own stumbles on Night 3 of the Republican confab. By Viveca Novak | factcheck. Video: Former New York Mayor Rudy Giuliani Full Speech at the RNC Palin packs a punch Publ.Date : Fri, 05 Sep 2008 00:41:06 GMT Cheney seeks to bolster Ukraine - BBC News
BBC News - US Vice-President Dick Cheney is in Ukraine on the last stop on his tour of the region aimed at showing support for US allies in the former Soviet Union. Video: Cheney Slams Russia for War Against Georgia Conflict in Georgia May Raise Pressure on Russia’s Oligarchs Publ.Date : Thu, 04 Sep 2008 18:52:03 GMT Gustav’s Rains Delay Cup Playoffs - New York Times
New York Times - By LARRY DORMAN ST. LOUIS - Torrential rain from the remnants of Hurricane Gustav drenched the Bellerive Country Club on Thursday and washed out the first round of the BMW Championship, the third of four events in the PGA Tour’s FedEx Cup playoffs. Hit the virtual green with new 'Tiger' golf game 'Tiger Woods' tops this season's golf games Publ.Date : Thu, 04 Sep 2008 23:09:34 GMT Increased Web Site Traffic |
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